Advanced immunochemical/Monoclonal mouse anti-human proinsulin/0.2 mg/1-pINS,Advanced immunochemical,,Advanced immunochemical lnc,advimmuno,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Advanced immunochemical/Monoclonal mouse anti-human proinsulin/0.2 mg/1-pINS

产品编号：1-pINS

市场价：¥4060.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>单克隆抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$203.00

品牌： Advanced immunochemical

公司：Advancedimmunochemical

公司分类：

商品介绍

General Category:

Monoclonal antibodies » Metabolic Syndrome

Disease Category:

Metabolic Syndrome » Monoclonal Antibodies

MAbs:

3A1, 1G4, 1D6Hybridoma clones have been derived from hybridization of X63-Ag8-653 myeloma cells with spleen cells of Balb/c mice immunized with purified human proinsulin.

Specificity:

MAbs 3A1 and 1G4 are directed to different antigenic determinants. MAb 3A1 reacts with the site of connection of C-peptide and C-end of B-chain of proinsulin molecule.MAbs 1D6 reacts with different epitopes on human proinsulin molecule; both of each are generated by the interactions between insulin and C-peptide parts of prohormone.Kd for MAb 3A1 is 1.1 x 10-8 M.Kd for MAb 1G4 is 2.6 x 10-7 M.Kd for MAb 1D6 is >3 x 10-8 M.MAbs 3A1, 1G4, 1D6 do not cross-react with human, bovine and porcine insulin,bovine and porcine proinsulin, and human C-peptide.

MAb Isotypes:

IgG1, kappa for all MAbs

Applications:

Detection of human proinsulin in two-site enzyme immunoassay.Recommended pairs for sandwich immunoassay (capture-detection):3A1 – 7F8 (Cat.#1-I1)1G4 – mixture of D6C4 and D3E7 (Cat.#1-IP)1D6 – 7F8, 8E2 (Cat.# 1-I1)D6C4 or D3E7 (Cat.#1-IP) (Could be used for direct coating of prohormone in serum samples)MAbs 3A1 and 1G4 can be used in immunohistochemistry on frozen sections.Specific immunosorbtional removal of proinsulin molecules (with immobilized 1D6 MAbs) from serum samples before the measurement of insulinic C-peptide.

Purification:

Chromatography on protein A Sepharose

Presentation:

PBS, pH 7.4, 0.1 % sodium azide (NaN3)

Storage Conditions:

+ 4 °C

Additional product information:

Rat C-peptide and proinsulin Assay Notes

References:

Search Proinsulin references from PubMed.See allInsulin, Proinsulin, C-peptide References

品牌介绍

Advanced ImmunoChemical以其在研究和临床诊断市场上提供高质量的ISO-9001：2015单克隆和多克隆抗体，抗原，酶和纯化的蛋白质而著称。我们几乎所有的产品均已通过验证，可用于定量夹心免疫分析和定性快速检测。